Review on Main Arboviruses Circulating on French Guiana, An Ultra-Peripheric European Region in South America

Timothee Bonifay (1) , Paul Le Turnier (1, 2) , Yanouk Epelboin (3) , Luisiane Carvalho (4) , Benoit de Thoisy (5) , Félix Djossou (2) , Jean-Bernard Duchemin (3) , Philippe Dussart (6) , Antoine Enfissi (7) , Anne Lavergne (5, 7) , Rémi Mutricy (2) , Mathieu Nacher (1) , Sébastien Rabier (1) , Stanislas Talaga (3) , Antoine Talarmin (8) , Dominique Rousset (7) , Loïc Epelboin (1, 2)

1 CIC - Antilles Guyane - Centre d'Investigation Clinique Antilles-Guyane
2 Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française]
3 Microbiote des insectes vecteurs / Microbiota of Insect Vectors [Cayenne, Guyane française]
4 Santé publique France Guyane
5 Laboratoire des Interactions Virus-Hôtes [Cayenne, Guyane Française]
6 Institut Pasteur de Madagascar
7 Laboratoire de virologie [Cayenne, Guyane française]
8 TReD-Path - Unité Transmission, Réservoir et Diversité des Pathogènes [Pasteur Guadeloupe, France]

French Guiana (FG), a French overseas territory in South America, is susceptible to tropical diseases, including arboviruses. The tropical climate supports the proliferation and establishment of vectors, making it difficult to control transmission. In the last ten years, FG has experienced large outbreaks of imported arboviruses such as Chikungunya and Zika, as well as endemic arboviruses such as dengue, Yellow fever, and Oropouche virus. Epidemiological surveillance is challenging due to the differing distributions and behaviors of vectors. This article aims to summarize the current knowledge of these arboviruses in FG and discuss the challenges of arbovirus emergence and reemergence. Effective control measures are hampered by the nonspecific clinical presentation of these diseases, as well as the Aedes aegypti mosquito’s resistance to insecticides. Despite the high seroprevalence of certain viruses, the possibility of new epidemics cannot be ruled out. Therefore, active epidemiological surveillance is needed to identify potential outbreaks, and an adequate sentinel surveillance system and broad virological diagnostic panel are being developed in FG to improve disease management.

Mots clés: arbovirus; French Guiana; Dengue virus; Chikungunya virus; Zika virus; Yellow fever virus; Mayaro virus; Tonate virus; Oropouche virus

Domaines: Sciences du Vivant [q-bio]

Timothee Bonifay, Paul Le Turnier, Yanouk Epelboin, Luisiane Carvalho, Benoit de Thoisy, et al.. Review on Main Arboviruses Circulating on French Guiana, An Ultra-Peripheric European Region in South America. Viruses, 2023, 15 (6), pp.1268. ⟨10.3390/v15061268⟩. ⟨pasteur-04109381⟩