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The relevance of different methods of calculating the ankle-brachial index: the multi-ethnic study of atherosclerosis.

Abstract : The authors aimed to determine differences in the prevalence of peripheral arterial disease (PAD) and its associations with cardiovascular disease (CVD) risk factors, using different methods of calculating the ankle-brachial index (ABI). Using measurements taken in the bilateral brachial, dorsalis pedis, and posterior tibial arteries, the authors calculated ABI in 3 ways: 1) with the lowest ankle pressure (dorsalis pedis artery or posterior tibial artery) ("ABI-LO"), 2) with the highest ankle pressure ("ABI-HI"), and 3) with the mean of the ankle pressures ("ABI-MN"). For all 3 methods, the index ABI was the lower of the ABIs calculated from the left and right legs. PAD was defined as an ABI less than 0.90. Among 6,590 subjects from a multiethnic cohort (baseline examination: 2000-2002), in comparison with ABI-HI, the relative prevalence of PAD was 3.95 times higher in women and 2.74 times higher in men when ABI-LO was used. The relative magnitudes of the associations were largest between PAD and both subclinical atherosclerosis and CVD risk factors when ABI-HI was used, except when risk estimates for PAD were less than 1.0, where the largest relative magnitudes of association were found using ABI-LO. PAD prevalence and its associations with CVD risk factors and subclinical atherosclerosis measures depend on the ankle pressure used to compute the ABI.
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https://hal-unilim.archives-ouvertes.fr/hal-00605413
Contributeur : Elisabeth Grelier <>
Soumis le : vendredi 1 juillet 2011 - 14:20:41
Dernière modification le : lundi 12 mars 2018 - 10:26:02

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Matthew A Allison, Victor Aboyans, Tanya Granston, Mary M Mcdermott, Aruna Kamineni, et al.. The relevance of different methods of calculating the ankle-brachial index: the multi-ethnic study of atherosclerosis.. American Journal of Epidemiology, Oxford University Press (OUP), 2010, 171 (3), pp.368-76. ⟨10.1093/aje/kwp382⟩. ⟨hal-00605413⟩

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