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Characteristics and outcome of patients hospitalised for lower extremity peripheral artery disease in France: the COPART Registry.

Abstract : OBJECTIVES: To assess the current 'real-world' management of hospitalised patients with lower-extremity peripheral artery disease (LE-PAD) and to assess the 1-year outcome. DESIGN, MATERIALS AND METHODS: The prospective and multicentre registry COhorte des Patients ARTériopathes (COPART) recruited consecutive patients from the departments of vascular medicine of three academic hospitals in Southwestern France. RESULTS: Among the 940 patients, 27.4% had intermittent claudication (IC), 9.3% ischaemic rest pain, 54.3% ulceration or gangrene and 9.3% acute limb ischaemia (ALI). Patients with IC were younger and more likely to be men, with a history of smoking (89.5%) and chronic obstructive pulmonary disease (17%). Among those with IC, 8.9% had bypass surgery and 41.5% were treated with percutaneous angioplasty. Those with tissue loss had higher rates of cardiovascular disease (CVD) risk factors and co-morbidities. At entry to the study, the level of control of the CVD risk factors was poor. The 1-year mortality rate was of 5.7% in patients with IC, 23.1% in patients with ischaemic rest pain, 28.7% in patients with tissue loss and 23% in those with ALI. Compliance with evidence-based medicine and pharmacological treatment was sub-optimal. CONCLUSION: This registry underscores the differences in patient profiles in the daily clinical setting, compared to those enrolled in several trials.
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https://hal-unilim.archives-ouvertes.fr/hal-00606139
Contributeur : Elisabeth Grelier <>
Soumis le : mardi 5 juillet 2011 - 15:03:47
Dernière modification le : dimanche 25 octobre 2020 - 07:04:57

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Jean Pierre Cambou, Victor Aboyans, J. Constans, Philippe Lacroix, C. Dentans, et al.. Characteristics and outcome of patients hospitalised for lower extremity peripheral artery disease in France: the COPART Registry.. European Journal of Vascular and Endovascular Surgery, Elsevier, 2010, 39 (5), pp.577-85. ⟨10.1016/j.ejvs.2010.02.009⟩. ⟨hal-00606139⟩

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