New photoantimicrobial films composed of porphyrinated lipophilic cellulose esters

Mohammed Krouit , Robert Granet (1) , Pierre Branland , Bernard Verneuil (1) , Pierre Krausz (1)

1 LCSN - Laboratoire de Chimie des Substances Naturelles

Porphyrinatedcellulose laurate esters have been prepared in homogeneous DMA/LiCl medium by 'one-pot, two-step' reactions starting from cellulose, protoporphyrin IX, and lauric acid and using a TsCl/Pyridine system. The plastic films obtained after casting were shown to display photobactericidal activity against Gram positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria. This new photobactericidal polymer has potential for industrial, medical, or household applications.

Domaines: Chimie organique

Mohammed Krouit, Robert Granet, Pierre Branland, Bernard Verneuil, Pierre Krausz. New photoantimicrobial films composed of porphyrinated lipophilic cellulose esters. Bioorganic and Medicinal Chemistry Letters, 2006, 16 (6), pp.1651-1655. ⟨10.1016/j.bmcl.2005.12.008⟩. ⟨hal-00684441⟩