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Synthesis and antiviral evaluation of AZT analogues with A spacer arm between glucidic and base moieties. Part II.

Abstract : This article describes the synthesis of a series of AZT analogues bearing an acyclic chain between the sugar and the base moieties is described. These new compounds were readily obtained using microwave irradiation. The compounds were characterized by (1)H NMR and IR spectroscopy. Antiviral (HIV-1) properties of these compounds were examined.
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https://hal-unilim.archives-ouvertes.fr/hal-00685483
Contributeur : Françoise Merigaud <>
Soumis le : jeudi 5 avril 2012 - 11:22:55
Dernière modification le : mardi 20 mars 2018 - 16:36:10

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Vincent Roy, Rachida Zerrouki, Pierre Krausz, Géraldine Laumond, Anne-Marie Aubertin. Synthesis and antiviral evaluation of AZT analogues with A spacer arm between glucidic and base moieties. Part II.. Nucleosides, Nucleotides and Nucleic Acids, Taylor & Francis, 2007, 26 (5), pp.413-421. ⟨10.1080/15257770701426153⟩. ⟨hal-00685483⟩

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