Synthesis and antiviral evaluation of AZT analogues with A spacer arm between glucidic and base moieties. Part II. - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Nucleosides, Nucleotides and Nucleic Acids Année : 2007

Synthesis and antiviral evaluation of AZT analogues with A spacer arm between glucidic and base moieties. Part II.

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Vincent Roy
Géraldine Laumond
  • Fonction : Auteur
Anne-Marie Aubertin
  • Fonction : Auteur
  • PersonId : 860359

Résumé

This article describes the synthesis of a series of AZT analogues bearing an acyclic chain between the sugar and the base moieties is described. These new compounds were readily obtained using microwave irradiation. The compounds were characterized by (1)H NMR and IR spectroscopy. Antiviral (HIV-1) properties of these compounds were examined.
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hal-00685483 , version 1 (05-04-2012)

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Vincent Roy, Rachida Zerrouki, Pierre Krausz, Géraldine Laumond, Anne-Marie Aubertin. Synthesis and antiviral evaluation of AZT analogues with A spacer arm between glucidic and base moieties. Part II.. Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (5), pp.413-421. ⟨10.1080/15257770701426153⟩. ⟨hal-00685483⟩
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