Rational design of sugar-based-surfactant combined catalysts for promoting glycerol as a solvent

Ayman Karam (1) , Nicolas Villandier (1) , Mathieu Delample (1) , Carmen Klein Koerkamp (2) , Jean-Paul Douliez (3) , Robert Granet (2) , Pierre Krausz (2) , Joël Barrault (1) , François Jerome (1)

1 LACCO - Laboratoire de catalyse en chimie organique
2 LCSN - Laboratoire de Chimie des Substances Naturelles
3 BIA - Unité de recherche sur les Biopolymères, Interactions Assemblages

Thumbnail image of graphical abstract A sugary treat: Here we report the great efficiency of sugar-based-surfactant combined catalysts for conducting selective base-catalyzed organic reactions in glycerol. Close control of the reaction selectivity was successfully obtained owing to the formation of catalytic hydrophobic pockets in glycerol (see figure). The advantages of our catalytic processes and its similarities with catalysis in water are also highlighted.

Mots clés: aminopolysaccharides; glycerol; green chemistry; homogeneous catalysis; solvent effects; surfactant combined catalysts

Domaines: Chimie organique

Ayman Karam, Nicolas Villandier, Mathieu Delample, Carmen Klein Koerkamp, Jean-Paul Douliez, et al.. Rational design of sugar-based-surfactant combined catalysts for promoting glycerol as a solvent. Chemistry - A European Journal, 2008, 14 (33), pp.10196-10200. ⟨10.1002/chem.200801495⟩. ⟨hal-00686757⟩