Synthesis and biological activity of chloroethyl pyrimidine nucleosides.

Ludovic Colombeau; Karine Teste; Amel Hadj-Bouazza; Vincent Chaleix; Rachida Zerrouki; Michel Kraemer; Odile Sainte-Catherine

doi:10.1080/15257770701795813

Article dans une revue

Synthesis and biological activity of chloroethyl pyrimidine nucleosides.

Ludovic Colombeau ¹ Karine Teste ¹ Amel Hadj-Bouazza ¹ Vincent Chaleix ¹ Rachida Zerrouki ¹ Michel Kraemer Odile Sainte-Catherine

1 LCSN - Laboratoire de Chimie des Substances Naturelles

Abstract : The synthesis and biological activity of chloroethyl pyrimidine nucleosides is presented. One of these new nucleosides analogues significantly inhibited cell proliferation, migration and invasion as tested in vitro on the A431 vulvar epidermal carcinoma cell line.

keyword : Nucleoside analogue microwave activation chloroethylnucleoside anticancer anti-migration anti-invasion

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Article dans une revue

Domaine :

Chimie / Chimie organique

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https://hal-unilim.archives-ouvertes.fr/hal-00686793
Contributeur : Françoise Merigaud <>
Soumis le : mercredi 11 avril 2012 - 11:28:24
Dernière modification le : mardi 20 mars 2018 - 16:36:17

Synthesis and biological activity of chloroethyl pyrimidine nucleosides.

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