Antimicrobial silver nanoparticles generated on cellulose nanocrystals

Nicolas Drogat (1) , Robert Granet (1) , Vincent Sol (1) , Abdelmajid Memmi (2) , Naïma Saad (1) , Carmen Klein Koerkamp (1) , Philippe Bressollier (1) , Pierre Krausz (1)

1 LCSN - Laboratoire de Chimie des Substances Naturelles
2 LATVPEP - Laboratoire d’analyse, de traitement et de valorisation des polluants de l’environnement et des produits [Monastir]

We describe a new approach to the formation of silver nanoparticles (Ag NPs) using cellulose nanocrystals. The process involves periodate oxidation of cellulose nanocrystals, generating aldehyde functions which, in turn, are used to reduce Ag+ into Ag0 in mild alkaline conditions. The nanoparticles were characterized using transmission electron microscopy (TEM) and ultraviolet-visible absorption spectroscopy. From the microscope studies (TEM) we observed that Ag NPs have spherical shape with a size distribution comprise between 20 and 45 nm. The antibacterial activity was assessed using the minimum inhibitory concentration. The antibacterial assays compare favourably with most of other experiments conducted with the same species.

Mots clés: Cellulose nanocrystals; Silver nanoparticles; Antimicrobial material; Colloidal suspension; Biomedicine

Domaines: Chimie organique

Nicolas Drogat, Robert Granet, Vincent Sol, Abdelmajid Memmi, Naïma Saad, et al.. Antimicrobial silver nanoparticles generated on cellulose nanocrystals. Journal of Nanoparticle Research, 2011, 13 (4), pp.1557-1562. ⟨10.1007/s11051-010-9995-1⟩. ⟨hal-00698485⟩