MRI and FDG PET/CT findings in a case of probable Heidenhain variant Creutzfeldt-Jakob disease.

Frédéric Clarençon (1) , F. Gutman , C. Giannesini , A. Pénicaud (2) , Damien Galanaud (3) , K. Kerrou (4) , B. Marro , J.-N. Talbot

1 ERMA - Equipe de Recherche Médicale Appliquée
2 CRPP - Centre de recherches Paul Pascal
3 CRMBM - Centre de résonance magnétique biologique et médicale
4 Service de médecine nucléaire [Paris 20eme]]

Creutzfeldt-Jakob disease (CJD) is a neurodegenerative disease caused by the accumulation of a pathogenic isoform of a prion protein in neurons that is responsible for subacute dementia. The Heidenhain variant is an atypical form of CJD in which visual signs are predominant. This is a report of the case of a 65-year-old man with probable CJD of the Heidenhain variant, with topographical concordance between findings on magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose (FDG) photopenic areas on positron emission tomography (PET)/computed tomography (CT) for cortical parietooccipital lesions.

Domaines: Sciences du Vivant [q-bio]; Neurosciences [q-bio.NC]

Frédéric Clarençon, F. Gutman, C. Giannesini, A. Pénicaud, Damien Galanaud, et al.. MRI and FDG PET/CT findings in a case of probable Heidenhain variant Creutzfeldt-Jakob disease.. Journal de Neuroradiologie / Journal of Neuroradiology, 2008, 35 (4), pp.240-3. ⟨10.1016/j.neurad.2008.03.001⟩. ⟨hal-00785238⟩