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Assessment of palliative care for advanced non-small-cell lung cancer in France: A prospective observational multicenter study (GFPC 0804 study).

Abstract : INTRODUCTION: Few studies assessed, in real life, symptoms, specific interventions and factors influencing palliative care (PC) initiation for patients with advanced non-small-cell lung cancer (NSCLC). The objective of this study was to examine, in a prospective cohort of advanced NSCLC patients, PC use and factors associated with early (≤3 months after diagnosis) PC initiation. METHODS: It was an observational multicenter study. Each center included 10 consecutive patients with PC initiation. RESULTS: 514 patients were enrolled by 39 centers (age: 62.3±10.7 years, performance status: 0/1; 68.6% cases). At baseline, the most frequent symptoms concerned pain (43.6%), malnutrition (37%) and psychological disorders (25.3%). Specific interventions were infrequent for pain control and malnutrition, but were more numerous for psychological and social problems and terminal care. Median time between diagnosis and PC initiation was 35 [13-84] days, median PC duration was 4.2 [0.6-9.3] months. Median overall survival was 8.6 [6.6-10.7] months; median survival after PC initiation was 3.6 [3.2-4.5] months. In multivariate analysis, only PS ≥2 was linked to early PC. CONCLUSION: This study showed that early PC initiation is not a standard for patients with advanced NSCLC.
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https://hal-unilim.archives-ouvertes.fr/hal-00861552
Contributeur : Jean-Christophe Daviet <>
Soumis le : vendredi 13 septembre 2013 - 08:44:12
Dernière modification le : mardi 20 octobre 2020 - 10:53:38

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Alain Vergnenègre, Stéphane Hominal, Achille Edem Tchalla, Henri Bérard, Isabelle Monnet, et al.. Assessment of palliative care for advanced non-small-cell lung cancer in France: A prospective observational multicenter study (GFPC 0804 study).. Lung Cancer, Elsevier, 2013, 82 (2), pp.353-7. ⟨10.1016/j.lungcan.2013.07.014⟩. ⟨hal-00861552⟩

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