Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.

Abstract : The presence of intralesional natural regulatory T cells, characterized by the expression of Foxp3 mRNA, was analyzed in patients with localized leishmaniasis due to Leishmania guyanensis infection that was unresponsive to treatment with pentamidine isethionate. Foxp3 mRNA levels were associated with unresponsiveness to treatment among patients with a lesion duration of 1 month, but this association was not observed among patients with a lesion duration of <1 month. In conclusion, high intralesional expression of Foxp3 might be an indicator of poor response to treatment, depending on the duration of lesions.
Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal-unilim.archives-ouvertes.fr/hal-00911620
Contributeur : Philippe Sindou <>
Soumis le : vendredi 29 novembre 2013 - 14:49:06
Dernière modification le : vendredi 15 mai 2020 - 17:28:08

Lien texte intégral

Identifiants

Collections

Citation

Eliane Bourreau, Catherine Ronet, Edith Darsissac, Marie-Claire Lise, Dominique Sainte Marie, et al.. In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.. Journal of Infectious Diseases, Oxford University Press (OUP), 2009, 199 (4), pp.576-9. ⟨10.1086/596508⟩. ⟨hal-00911620⟩

Partager

Métriques

Consultations de la notice

148