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Communication dans un congrès

Optical designs for multimodal nonlinear microendoscope for optical biopsy

Abstract : Linear and nonlinear optical imaging systems are currently being miniaturized to fit endoscopic size requirements of a diameter less than 2 mm. These systems are used for deep imaging and optical biopsy. We report our progress in the development of a multimodal microendoscope based on Gradient Index (GRIN) lenses and double clad fiber (DCF) for femtosecond pulse delivery and signal collection. Four commercial DCFs were identified from the literature and our choice was based on the simulation results for optimal pulse delivery -needed for efficient 2-photon excitation- and optimal fluorescence signal collection. The pulse delivery simulation was done using a GRISM line system for compensating linear and nonlinear effects inside the DCF. The effect of GRIN lens aberration on collection efficiency was estimated by simulation using Zemax. GRIN lenses were also validated for fluorescence lifetime, spectroscopic measurement and mouse tissue imaging.
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Communication dans un congrès
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Contributeur : Claire Lefort Connectez-vous pour contacter le contributeur
Soumis le : jeudi 5 décembre 2013 - 17:39:55
Dernière modification le : dimanche 26 juin 2022 - 12:00:15




Hussein Hamzeh, Claire Lefort, Jamal Charara, Frédéric Louradour, Gael Latour, et al.. Optical designs for multimodal nonlinear microendoscope for optical biopsy. Advances in Biomedical Engineering (ICABME), 2013, Sep 2013, Tripoli, Lebanon. pp.155-158, ⟨10.1109/ICABME.2013.6648871⟩. ⟨hal-00914648⟩



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