First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania.

Carmen Anca Costache , Horaţiu Alexandru Colosi , Ligia Blaga , Adriana Györke , Anamaria Ioana Paştiu , Ioana Alina Colosi , Daniel Ajzenberg (1, 2, 3)

1 NET - Neuroépidémiologie Tropicale
2 CNR Toxoplasmose-Toxoplasma BRC - Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Resource Center (BRC)
3 UNILIM - Université de Limoges

Very limited data exists on the genetic diversity of Toxoplasma gondii from Eastern Europe. We present the first Romanian case of symptomatic congenital toxoplasmosis in which the T. gondii strain was isolated after inoculation in mice of a cerebrospinal fluid sample from a living neonate. The T. gondii strain was genotyped with 15 microsatellite markers distributed on 10 of the 14 chromosomes of T. gondii. The strain had a type II genotype.

Domaines: Santé publique et épidémiologie

Carmen Anca Costache, Horaţiu Alexandru Colosi, Ligia Blaga, Adriana Györke, Anamaria Ioana Paştiu, et al.. First isolation and genetic characterization of a Toxoplasma gondii strain from a symptomatic human case of congenital toxoplasmosis in Romania.. Parasite, 2013, 20, pp.11. ⟨10.1051/parasite/2013011⟩. ⟨hal-00925463⟩