Laboratory-based surveillance for Cryptosporidium in France, 2006-2009.

Karine Guyot (1, 2) , Francis Derouin (1) , Patrice Agnamey (1, 3) , Adela Angoulvant (1) , D. Aubert (1) , C. Aznar (1, 4) , Didier Basset (1, 5) , Pascal Beaudeau (1, 6) , G. Belkadi (1) , A. Berry (1) , Alain Bonnin (1, 7) , Françoise Botterel (1, 8) , M.-E. Bougnoux (1, 9) , Patrice Bourée (1, 10) , Pierre Buffet (1, 11, 12) , M. Cambon (1) , Bernard Carme (1, 13, 4) , Gabriela Certad (2, 1) , C. Chartier (1) , B. Couprie (1) , Frédéric Dalle (1, 7) , E. Dannaoui (1, 14) , Marie-Laure Dardé (1, 15, 16, 17) , E. Dei Cas (1) , B. Degeilh (1) , Nicole Desbois (1, 18) , Jean-Marc Dewitte (1) , C. Duhamel (1) , T.H. Duong (1) , J. Dupouy-Camet (1) , Alexandra Faussart (1) , L. Favennec (1) , Pierre Flori (1, 19) , N. Gantois (1) , G. Gargala (1, 20) , Frédéric Grenouillet (1, 21) , Ml Grillot (1) , D. Haouchine (1) , Sandrine Houzé (1)

1 Anofel Cryptosporidium National Network
2 CIIL - Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204
3 Service des maladies infectieuses et tropicales [Rouen]
4 Laboratoire Hospitalo-Universitaire de Parasitologie-Mycologie
5 Laboratoire de Parasitologie-Mycologie
6 Département santé environnement
7 CHU Dijon
8 Laboratoire de Parasitologie-Mycologie
9 CHU Necker - Enfants Malades [AP-HP]
10 Service de parasitologie
11 Service de Parasitologie - Mycologie [CHU Pitié-Salpétrière]
12 Immunité et Infection
13 Epidémiologie des parasitoses et mycoses tropicales
14 Hôpital Européen Georges Pompidou
15 CNR Toxoplasmose-Toxoplasma BRC - Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Resource Center (BRC)
16 UNILIM - Université de Limoges
17 NETEC - Neuroépidémiologie Tropicale et Comparée
18 Parasitologie-Mycologie Fort de France
19 GIMAP - Groupe Immunité des Muqueuses et Agents Pathogènes
20 ADEN - Appareil Digestif Environnement Nutrition
21 LCE - Laboratoire Chrono-environnement (UMR 6249)

In 2002, the French Food Safety Agency drew attention to the lack of information on the prevalence of human cryptosporidiosis in the country. Two years later, the ANOFEL Cryptosporidium National Network (ACNN) was set up to provide public health authorities with data on the incidence and epidemiology of human cryptosporidiosis in France. Constituted on a voluntary basis, ACNN includes 38 hospital parasitology laboratories (mainly in university hospitals). Each laboratory is engaged to notify new cases of confirmed human cryptosporidiosis, store specimens (e.g. stools, duodenal aspirates or biopsies) and related clinical and epidemiological data, using data sheet forms. From January 2006 to December 2009, 407 cryptosporidiosis cases were notified in France and 364 specimens were collected. Of the notified cases, 74 were children under four years of age, accounting for 18.2%. HIV-infected and immunocompetent patients represented 38.6% (n=157) and 28% (n=114) of cases, respectively. A marked seasonal pattern was observed each year, with increased number of cases in mid to late summer and the beginning of autumn. Genotyping of 345 isolates from 310 patients identified C. parvumin 168 (54.2%) cases, C. hominis in 113 (36.4%) and other species in 29 (9.4%), including C. felis (n=15), C. meleagridis (n=4), C. canis (n=4), Cryptosporidium chipmunk genotype (n=1), Cryptosporidium rabbit genotype (n=1) and new Cryptosporidium genotypes (n=4). These data represent the first multisite report of laboratory-confirmed cases of cryptosporidiosis in France.

Domaines: Santé publique et épidémiologie

Karine Guyot, Francis Derouin, Patrice Agnamey, Adela Angoulvant, D. Aubert, et al.. Laboratory-based surveillance for Cryptosporidium in France, 2006-2009.. Eurosurveillance, 2010, 15 (33), pp.19642. ⟨10.2807/ese.15.33.19642-en⟩. ⟨hal-00926813⟩