Use Of SCO-Spondin Peptides For Inhibiting Or Preventing Neuronal Apoptosis Mediated By Cell Death Receptor Ligands - Archive ouverte HAL Accéder directement au contenu
Brevet Année : 2011

Use Of SCO-Spondin Peptides For Inhibiting Or Preventing Neuronal Apoptosis Mediated By Cell Death Receptor Ligands

(1)
1

Résumé

The invention relates to a polypeptide derived from the TSR (thrombospondin type 1 units) of SCO-Spondin for inhibiting or preventing the apoptosis mediated by the cell death receptor ligands, such as TRAIL or FasL. The polypeptide of the invention comprises a sequence -W-S-A1-C-S-A2-C-G- wherein A1 and A2 are amino acid sequences comprising 1 to 5 amino acids. More particularly, the invention relates to said polypeptide for inhibiting or preventing the apoptosis associated with a disease selected from the group consisting of neurodegenerative disorders, cerebral ischemia, neuronal traumas, neuronal inflammatory diseases, and viral neurodegenerations.
Fichier non déposé

Dates et versions

hal-00938266 , version 1 (29-01-2014)

Identifiants

  • HAL Id : hal-00938266 , version 1

Citer

Annie Meiniel. Use Of SCO-Spondin Peptides For Inhibiting Or Preventing Neuronal Apoptosis Mediated By Cell Death Receptor Ligands. Patent n° : US2011178023. 2011. ⟨hal-00938266⟩
43 Consultations
0 Téléchargements

Partager

Gmail Facebook Twitter LinkedIn More