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Article Dans Une Revue Bioorganic and Medicinal Chemistry Letters Année : 2016

Development of curcumin-cyclodextrin/cellulose nanocrystals complexes: New anticancer drug delivery systems

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Résumé

The synthesis of curcumin-cyclodextrin/cellulose nanocrystals (CNCx) nano complexes was performed. CNCx were functionalized by ionic association with cationic β-cyclodextrin (CD) and CD/CNCx complexes were used to encapsulate curcumin. Preliminary in vitro results showed that the resulting curcumin-CD/CNCx complexes exerted antiproliferative effect on colorectal and prostatic cancer cell lines, with IC50s lower than that of curcumin alone.
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Dates et versions

hal-01257118 , version 1 (15-01-2016)

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Gautier Mark Arthur Ndong Ntoutoume, Robert Granet, Jean-Pierre Mbakidi, Frédérique Brégier, David Yannick Leger, et al.. Development of curcumin-cyclodextrin/cellulose nanocrystals complexes: New anticancer drug delivery systems. Bioorganic and Medicinal Chemistry Letters, 2016, 26, pp.941-945. ⟨10.1016/j.bmcl.2015.12.060⟩. ⟨hal-01257118⟩
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