[Medicines and frailty in older people. Towards a new nosological entity: A pharmacological frailty?].

Hichem Nessighaoui (1) , Hélène Géniaux , Thierry Dantoine (1) , Marie-Laure Laroche (1, 2)

1 HAVAE - Handicap, Activité, Vieillissement, Autonomie, Environnement
2 Service de Pharmacologie, toxicologie et pharmacovigilance [CHU Limoges]

Frailty is a complex geriatric syndrome linked to the overall decrease of physiological reserves. It could lead to disability and to an increase in mortality. Frailty could have an impact on the effect and on the use of medications. Drugs could also affect the frailty process. Currently, no specific guidelines exist for appropriately prescribing medications to frail older people. The aim of this paper is to explore the body of current knowledge about the relationship between drugs and frailty in older people and to introduce a new nosological entity: pharmacological frailty.

Domaines: Médecine humaine et pathologie

Hichem Nessighaoui, Hélène Géniaux, Thierry Dantoine, Marie-Laure Laroche. [Medicines and frailty in older people. Towards a new nosological entity: A pharmacological frailty?].. Thérapie, 2016, 71 (3), pp.275-9. ⟨hal-01346669⟩