Evidence for early infection of nonneoplastic natural killer cells by Epstein-Barr virus.

Abstract : We examined lymph nodes and tonsils from patients with infectious mononucleosis by combined detection of EBV-encoded RNA and a specific marker of natural killer (NK) cells, PEN5. A small number of Epstein-Barr virus (EBV) latently infected nonneoplastic NK cells were detected. Our data demonstrate that NK cells are natural targets of EBV and that infection of these cells is an early event observed during primary EBV infection.
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Contributeur : Nathalie Faumont <>
Soumis le : jeudi 5 avril 2018 - 15:02:57
Dernière modification le : lundi 20 mai 2019 - 15:32:02

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Pascal Trempat, Julie Tabiasco, Pascale Andre, Nathalie Faumont, Fabienne Meggetto, et al.. Evidence for early infection of nonneoplastic natural killer cells by Epstein-Barr virus.. Journal of Virology, American Society for Microbiology, 2002, pp.11139-11142. ⟨10.1128/JVI.76.21.11139-11142.2002⟩. ⟨hal-01759549⟩

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