Global cancer statistics, CA: A Cancer Journal for Clinicians, vol.82, issue.19 suppl, pp.69-90, 2011. ,
DOI : 10.1097/00002030-199912240-00012
Colorectal cancer and the 7th revision of the TNM staging system: review of changes and suggestions for uniform pathologic reporting, Romanian J Morphol Embryol Rev Roum Morphol Embryol, vol.52, pp.537-581, 2011. ,
Drug Resistance in Cancer: An Overview, Cancers, vol.6, issue.3, pp.1769-92, 2014. ,
DOI : 10.4137/GEG.S12270
URL : http://www.mdpi.com/2072-6694/6/3/1769/pdf
IN VITRO AND IN VIVO EFFECTS OF A NERVE GROWTH-STIMULATING AGENT ISOLATED FROM SNAKE VENOM, Proceedings of the National Academy of Sciences, vol.42, issue.9, pp.695-704, 1956. ,
DOI : 10.1073/pnas.42.9.695
Trk receptors: mediators of neurotrophin action, Current Opinion in Neurobiology, vol.11, issue.3, pp.272-80, 2001. ,
DOI : 10.1016/S0959-4388(00)00208-7
Neurotrophin Signaling via Trks and p75, Experimental Cell Research, vol.253, issue.1, pp.131-173, 1999. ,
DOI : 10.1006/excr.1999.4705
Fine-Tuning Roles of Endogenous Brain-Derived Neurotrophic Factor, TrkB and Sortilin in Colorectal Cancer Cell Survival, PLoS ONE, vol.124, issue.9, p.25097, 2011. ,
DOI : 10.1371/journal.pone.0025097.t003
URL : https://hal.archives-ouvertes.fr/hal-00873136
Tyrosine kinase B receptor and BDNF expression in ovarian cancers ??? Effect on cell migration, angiogenesis and clinical outcome, Cancer Letters, vol.281, issue.2, pp.151-61, 2009. ,
DOI : 10.1016/j.canlet.2009.02.025
The PI3K/AKT/mTOR pathway is a potential predictor of distinct invasive and migratory capacities in human ovarian cancer cell lines, Oncotarget, vol.6, issue.28, pp.25520-25552, 2015. ,
DOI : 10.18632/oncotarget.4550
,
, Anti-apoptotic role and clinical relevance of neurotrophins in diffuse large B-cell lymphomas, Br J Cancer, vol.113, pp.934-978, 2015.
BDNF mediated TrkB activation contributes to the EMT progression and the poor prognosis in human salivary adenoid cystic carcinoma, Oral Oncology, vol.51, issue.1, pp.64-70, 2015. ,
DOI : 10.1016/j.oraloncology.2014.10.008
Induction of metastatic potential by TrkB via activation of IL6/JAK2/STAT3 and PI3K/AKT signaling in breast cancer, Oncotarget, vol.6, issue.37, pp.40158-71, 2015. ,
DOI : 10.18632/oncotarget.5522
Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells, Clin Cancer Res Off J Am Assoc Cancer Res, vol.11, pp.440-449, 2005. ,
Tyrosine receptor kinase B silencing inhibits anoikis-resistance and improves anticancer efficiency of sorafenib in human renal cancer cells, International Journal of Oncology, vol.48, issue.4, pp.1417-1442, 2016. ,
DOI : 10.3892/ijo.2016.3356
BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer, Oncology, vol.62, issue.5-6, pp.430-439, 2010. ,
DOI : 10.2174/092986609788490177
Tropomyosin-related kinase B/brain derived-neurotrophic factor signaling pathway as a potential therapeutic target for colorectal cancer, World Journal of Gastroenterology, vol.22, issue.2, pp.490-500, 2016. ,
DOI : 10.1002/jso.20785
BDNF/TrkB signaling as an anti-tumor target, Expert Review of Anticancer Therapy, vol.17, issue.10, pp.1473-1478, 2011. ,
DOI : 10.1158/1078-0432.CCR-10-2802
K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors, Oncogene, vol.7, pp.371-81, 1992. ,
Trk inhibition reduces cell proliferation and potentiates the effects of chemotherapeutic agents in Ewing sarcoma, Oncotarget, vol.7, issue.23, pp.34860-80, 2016. ,
DOI : 10.18632/oncotarget.8992
The pleiotropic role of autophagy: from protein metabolism to bactericide, Cell Death and Differentiation, vol.34, pp.1535-1576, 2005. ,
DOI : 10.1016/0005-2787(77)90005-3
URL : http://www.nature.com/cdd/journal/v12/n2s/pdf/4401728a.pdf
Autophagy mediates phase transitions from cell death to life, Heliyon, vol.1, issue.1, p.27, 2015. ,
DOI : 10.1016/j.heliyon.2015.e00027
URL : https://doi.org/10.1016/j.heliyon.2015.e00027
Autophagy and the Integrated Stress Response, Molecular Cell, vol.40, issue.2, pp.280-93, 2010. ,
DOI : 10.1016/j.molcel.2010.09.023
URL : https://doi.org/10.1016/j.molcel.2010.09.023
Autophagy: a new concept in cancer research, Bull Cancer (Paris), vol.95, pp.43-50, 2008. ,
LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing, The EMBO Journal, vol.19, issue.21, pp.5720-5728, 2000. ,
DOI : 10.1093/emboj/19.21.5720
URL : http://emboj.embopress.org/content/embojnl/19/21/5720.full.pdf
Guidelines for the use and interpretation of assays for monitoring autophagy, Autophagy, vol.4, issue.4, pp.1-222, 2016. ,
DOI : 10.4161/auto.6.4.12244
URL : https://hal.archives-ouvertes.fr/hal-01343085
Autophagy in malignant transformation and cancer progression, The EMBO Journal, vol.34, issue.7, pp.856-80, 2015. ,
DOI : 10.15252/embj.201490784
URL : http://emboj.embopress.org/content/embojnl/34/7/856.full.pdf
Autophagy in colorectal cancer: An important switch from physiology to pathology, World Journal of Gastrointestinal Oncology, vol.7, issue.11, pp.271-84, 2015. ,
DOI : 10.4251/wjgo.v7.i11.271
URL : http://europepmc.org/articles/pmc4644850?pdf=render
Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress, BMC Cancer, vol.456, issue.7219, p.795, 2015. ,
DOI : 10.1038/nature07383
URL : https://bmccancer.biomedcentral.com/track/pdf/10.1186/s12885-015-1789-5?site=bmccancer.biomedcentral.com
Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells, BMC Cancer, vol.374, issue.2, p.370, 2010. ,
DOI : 10.1016/j.bbrc.2008.07.031
URL : https://bmccancer.biomedcentral.com/track/pdf/10.1186/1471-2407-10-370?site=bmccancer.biomedcentral.com
Inhibition of autophagy promotes apoptosis and enhances anticancer efficacy of adriamycin via augmented ROS generation in prostate cancer cells, The International Journal of Biochemistry & Cell Biology, vol.77, pp.80-90, 2016. ,
DOI : 10.1016/j.biocel.2016.05.020
Intestinal inhibition of Atg7 prevents tumour initiation through a microbiome-influenced immune response and suppresses tumour growth, Nat Cell Biol, vol.17, pp.1062-73, 2015. ,
, Journal of Cellular and Molecular Medicine, p.2621
, J. Cell. Mol. Med, vol.21, issue.10, p.2017
Inhibition of Brain-Derived Neurotrophic Factor/Tyrosine Kinase B Signaling Suppresses Choriocarcinoma Cell Growth, Endocrinology, vol.151, issue.7, pp.3006-3020, 2010. ,
DOI : 10.1210/en.2009-1378
Inhibition of autophagy as a new means of improving chemotherapy efficiency in high-LC3B triple-negative breast cancers, Autophagy, vol.61, issue.12, pp.2122-2164, 2015. ,
DOI : 10.4161/auto.4451
New ex-ovo colorectal-cancer models from different SdFFF-sorted tumour-initiating cells, Anal Bioanal Chem, vol.407, pp.8433-8476, 2015. ,
Implications of cleaved caspase 3 and AIF expression in colorectal cancer based on patient age, Oncology Reports, vol.27, pp.1787-93, 2012. ,
DOI : 10.3892/or.2012.1737
URL : https://hal.archives-ouvertes.fr/hal-00873114
Role of Endogenous Brain-Derived Neurotrophic Factor and Sortilin in B Cell Survival, The Journal of Immunology, vol.181, issue.5, pp.3027-3065, 1950. ,
DOI : 10.4049/jimmunol.181.5.3027
URL : https://hal.archives-ouvertes.fr/hal-00453223
Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Are Expressed in Breast Cancer and Can Be Targeted to Inhibit Tumor Cell Survival, Clinical Cancer Research, vol.17, issue.7, pp.1741-52, 2011. ,
DOI : 10.1158/1078-0432.CCR-10-1890
Brain-Derived Neurotrophic Factor (BDNF)-Induced Tropomyosin-Related Kinase B (Trk B) Signaling Is a Potential Therapeutic Target for Peritoneal Carcinomatosis Arising from Colorectal Cancer, PLoS ONE, vol.56, issue.79, p.96410, 2014. ,
DOI : 10.1371/journal.pone.0096410.t001
URL : https://doi.org/10.1371/journal.pone.0096410
K-252a and staurosporine selectively block autophosphorylation of neurotrophin receptors and neurotrophin-mediated responses., Molecular Biology of the Cell, vol.3, issue.6 ,
DOI : 10.1091/mbc.3.6.677
URL : http://europepmc.org/articles/pmc275622?pdf=render
, Mol Biol Cell, vol.3, pp.677-86, 1992.
Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient Deprivation, Cancer Research, vol.67, issue.20, pp.9677-84, 2007. ,
DOI : 10.1158/0008-5472.CAN-07-1462
Application and interpretation of current autophagy inhibitors and activators, Acta Pharmacologica Sinica, vol.17, issue.5, pp.625-660, 2013. ,
DOI : 10.1093/hmg/ddm294
URL : https://www.nature.com/articles/aps20135.pdf
Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer, Lung Cancer, vol.81, issue.3, pp.354-61, 2013. ,
DOI : 10.1016/j.lungcan.2013.05.012
Colorectal cancer cells are resistant to anti-EGFR monoclonal antibody through adapted autophagy, Am J Transl Res, vol.8, pp.1190-1196, 2016. ,
Autophagy as a target for anticancer therapy, Nature Reviews Clinical Oncology, vol.4, issue.9, pp.528-567, 2011. ,
DOI : 10.4161/auto.5338
EGFR inhibitors and autophagy in cancer treatment, Tumor Biology, vol.17, issue.43, pp.11701-11710, 2014. ,
DOI : 10.3748/wjg.v17.i43.4779
Time to use a dose of Chloroquine as an adjuvant to anti-cancer chemotherapies, European Journal of Pharmacology, vol.771, pp.139-183, 2016. ,
DOI : 10.1016/j.ejphar.2015.12.017
Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?, Cancer Cell International, vol.8, issue.1, p.62, 2016. ,
DOI : 10.1038/nrc2442
Validation of a model of colon cancer progression, The Journal of Pathology, vol.192, issue.4, pp.446-54, 2000. ,
DOI : 10.1038/bjc.1995.55
High TrkB expression levels are associated with poor prognosis and EMT induction in colorectal cancer cells, Journal of Gastroenterology, vol.12, issue.7, pp.775-84, 2012. ,
DOI : 10.1158/1078-0432.CCR-06-0038
Tumor Heterogeneity: Mechanisms and Bases for a Reliable Application of Molecular Marker Design, International Journal of Molecular Sciences, vol.19, issue.2, pp.1951-2011, 2012. ,
DOI : 10.1093/annonc/mdn021
Tropomyosin-related kinase B promotes distant metastasis of colorectal cancer through protein kinase B-mediated anoikis suppression and correlates with poor prognosis, Apoptosis, vol.17, issue.5, pp.860-70, 2014. ,
DOI : 10.1038/sj.onc.1203598
Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas, Journal of Clinical Pathology, vol.63, issue.10, pp.867-72, 2010. ,
DOI : 10.1136/jcp.2010.079525
, Journal of Cellular and Molecular Medicine