S. Bayer, . Bms/pfizer, . Amgen, M. Novartis, and . Sevestre, Bayer, BMS/Pfzer, Aspen et LeoPharma. Les autres auteurs déclarent ne pas avoir de liens d'intérêts

. Références,

F. G. Fowkes, D. Rudan, I. Rudan, V. Aboyans, J. O. Denenberg et al., Comparison of global estimates of prevalence and risk factors for peripheral artery disease in 2000 and 2010: a systematic review and analysis, Lancet, vol.382, pp.1329-1369, 2013.
URL : https://hal.archives-ouvertes.fr/hal-00925590

F. G. Fowkes, V. Aboyans, F. J. Fowkes, M. M. Mcdermott, U. K. Sampson et al., Peripheral artery disease: epidemiology and global perspectives, Nat Rev Cardiol, vol.14, pp.156-70, 2017.

M. H. Criqui and V. Aboyans, Epidemiology of peripheral artery disease, Circ Res, vol.116, pp.1509-1535, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01233163

M. H. Criqui, R. D. Langer, A. Fronek, H. S. Feigelson, M. R. Klauber et al., Mortality over a period of 10 years in patients with peripheral arterial disease, N Engl J Med, vol.326, pp.381-387, 1992.

F. G. Fowkes, G. D. Murray, I. Butcher, C. L. Heald, R. J. Lee et al., Ankle-brachial index combined with Framingham Risk Score to predict cardiovascular events and mortality: a meta-analysis, JAMA, vol.300, pp.197-208, 2008.

V. Aboyans, M. H. Criqui, P. Abraham, M. A. Allison, M. A. Creager et al., Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association, Circulation, vol.126, pp.2890-909, 2012.
URL : https://hal.archives-ouvertes.fr/hal-00921590

J. G. Lijmer, M. G. Hunink, J. J. Van-den-dungen, J. Loonstra, and A. J. Smit, ROC analysis of noninvasive tests for peripheral arterial disease, Ultrasound Med Biol, vol.22, pp.391-399, 1996.

V. Aboyans, M. H. Criqui, R. L. Mcclelland, M. A. Allison, M. M. Mcdermott et al., Intrinsic contribution of gender and ethnicity to normal ankle-brachial index values: the Multi-Ethnic Study of, Atherosclerosis

, J Vasc Surg, vol.45, pp.319-346, 2007.

V. Aboyans, P. Lacroix, W. Waruingi, F. Bertin, F. Pesteil et al., Traduction française et validation du questionnaire d'Edimbourg pour le diagnostic de la claudication intermittente, Arch Mal Coeur Vaiss, vol.93, pp.1173-1180, 2000.

D. P. Brostow, M. L. Petrik, A. J. Starosta, and S. W. Waldo, Depression in patients with peripheral arterial disease: a systematic review, Eur J Cardiovasc Nurs, vol.16, pp.181-93, 2017.

U. K. Sampson, F. G. Fowkes, M. M. Mcdermott, M. H. Criqui, V. Aboyans et al., Global and regional burden of death and disability from peripheral artery disease: 21 world regions, Glob Heart, vol.9, pp.145-58, 1990.

I. Desormais, V. Aboyans, M. Guerchet, B. Ndamba-bandzouzi, P. Mbelesso et al., Prevalence of peripheral artery disease in the elderly population in urban and rural areas of Central Africa: the EPIDEMCA study, Eur J Prev Cardiol, vol.22, pp.1462-72, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01235006

L. Norgren, W. R. Hiatt, J. A. Dormandy, M. R. Nehler, K. A. Harris et al., Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II), Eur J Vasc Endovasc Surg, vol.33, pp.1-75, 2007.

H. E. Stoffers, P. E. Rinkens, A. D. Kester, V. Kaiser, and J. A. Knottnerus, The prevalence of asymptomatic and unrecognized peripheral arterial occlusive disease, Int J Epidemiol, vol.25, pp.282-90, 1996.

M. Nehler, S. Duval, L. Diao, B. H. Annex, W. R. Hiatt et al., Epidemiology of peripheral arterial disease and critical limb ischemia in an insured national population, J Vasc Surg, vol.60, pp.686-95, 2014.

B. Sigvant, K. Wiberg-hedman, D. Bergqvist, O. Rolandsson, B. Andersson et al., A population-based study of peripheral arterial disease prevalence with special focus on critical limb ischaemia and sex differences, J Vasc Surg, vol.45, pp.1185-91, 2007.

I. O. Ingolfsson, G. Sigurdsson, H. Sigvaldason, G. Thorgeirsson, and N. Sigfusson, A marked decline in the prevalence and incidence of intermittent claudication in Icelandic men 1968-1986: a strong relationship to smoking and serum cholesterol -the Reykjavik Study, J Clin Epidemiol, vol.47, pp.1237-1280, 1994.

S. J. Bowlin, J. H. Medalie, S. A. Flocke, S. J. Zyzanski, and U. Goldbourt, Epidemiology of intermittent claudication in middle-aged men, Am J Epidemiol, vol.140, pp.418-448, 1994.

W. B. Kannel and D. L. Mcgee, Update on some epidemiologic features of intermittent claudication: the Framingham Study, J Am Geriatr Soc, vol.33, pp.13-21, 1985.

P. M. Rothwell, A. J. Coull, L. E. Silver, J. F. Fairhead, M. F. Giles et al., Population-based study of event-rate, incidence, case fatality, and mortality for all acute vascular events in all arterial territories (Oxford Vascular Study), Lancet, vol.366, pp.1773-83, 2005.

, Epidemiology of lower extremity amputation in centres in Europe, Br J Surg, vol.87, pp.328-365, 2000.

K. Heyer, E. S. Debus, L. Mayerhoff, and A. M. , Prevalence and regional distribution of lower limb amputations from 2006 to 2012 in Germany: a population-based study, Eur J Vasc Endovasc Surg, vol.50, issue.6, pp.761-767, 2015.

E. Kolossvary, T. Ferenci, T. Kovats, L. Kovacs, Z. Jarai et al., Trends in major lower limb amputation related to peripheral arterial disease in Hungary: a nationwide study, Eur J Vasc Endovasc Surg, vol.50, pp.78-85, 2004.

J. P. Cambou, V. Aboyans, J. Constans, P. Lacroix, C. Dentans et al., Characteristics and outcome of patients hospitalised for lower extremity peripheral artery disease in France: the COPART Registry, Eur J Vasc Endovasc Surg, vol.39, pp.577-85, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00606139

M. M. Joosten, J. K. Pai, M. L. Bertoia, E. B. Rimm, D. Spiegelman et al., Associations between conventional cardiovascular risk factors and risk of peripheral artery disease in men, JAMA, vol.308, pp.1660-1667, 2012.

Y. He, T. H. Lam, B. Jiang, J. Wang, X. Sai et al., Passive smoking and risk of peripheral arterial disease and ischemic stroke in Chinese women who never smoked, Circulation, vol.118, pp.1535-1575, 2008.

J. M. Murabito, D. 'agostino, R. B. Silbershatz, H. Wilson, and W. F. , Intermittent claudication. A risk profile from The Framingham Heart Study, Circulation, vol.96, pp.44-53, 1997.

W. T. Meijer, D. E. Grobbee, M. G. Hunink, A. Hofman, and A. W. Hoes, Determinants of peripheral arterial disease in the elderly: the Rotterdam study, Arch Intern Med, vol.160, pp.2934-2942, 2000.

M. A. Allison, M. H. Criqui, R. L. Mcclelland, J. M. Scott, M. M. Mcdermott et al., The effect of novel cardiovascular risk factors on the ethnicspecific odds for peripheral arterial disease in the Multi-Ethnic Study of Atherosclerosis (MESA), J Am Coll Cardiol, vol.48, pp.1190-1197, 2006.

V. Aboyans, E. Ho, J. O. Denenberg, L. A. Ho, L. Natarajan et al., The association between elevated ankle systolic pressures and peripheral occlusive arterial disease in diabetic and nondiabetic subjects, J Vasc Surg, vol.48, pp.1197-203, 2008.

J. D. Curb, K. Masaki, B. L. Rodriguez, R. D. Abbott, C. M. Burchfiel et al., Peripheral artery disease and cardiovascular risk factors in the elderly, The Honolulu Heart Program. Arterioscler Thromb Vasc Biol, vol.16, pp.1495-500, 1996.

J. Ness, W. S. Aronow, and C. Ahn, Risk factors for symptomatic peripheral arterial disease in older persons in an academic hospital-based geriatrics practice, J Am Geriatr Soc, vol.48, pp.312-316, 2000.

P. M. Ridker, M. J. Stampfer, and N. Rifai, Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease, JAMA, vol.285, pp.2481-2486, 2001.

D. J. Kumbhani, P. G. Steg, C. P. Cannon, K. A. Eagle, S. Jr et al., Statin therapy and long-term adverse limb outcomes in patients with peripheral artery disease: insights from the REACH registry, Eur Heart J, vol.35, pp.2864-72, 2014.

G. D. Lowe, F. G. Fowkes, J. Dawes, P. T. Donnan, S. E. Lennie et al., Blood viscosity, fibrinogen, and activation of coagulation and leukocytes in peripheral arterial disease and the normal population in the Edinburgh Artery Study, Circulation, vol.87, pp.1915-1935, 1993.

V. Aboyans, M. H. Criqui, J. O. Denenberg, J. D. Knoke, P. M. Ridker et al., Risk factors for progression of peripheral arterial disease in large and small vessels, Circulation, vol.113, pp.2623-2632, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00354988

J. W. Knowles, T. L. Assimes, J. Li, T. Quertermous, and J. P. Cooke, Genetic susceptibility to peripheral arterial disease: a dark coroner in vascular biology, Arterioscler Thromb Vasc Biol, vol.27, pp.2068-78, 2007.

C. L. Wassel, C. Lamina, V. Nambi, S. Coassin, K. J. Mukamal et al., Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium, Atherosclerosis, vol.222, pp.138-185, 2012.

R. L. Pande and M. A. Creager, Socioeconomic inequality and peripheral artery disease prevalence in US adults, Circ Cardiovasc Qual Outcomes, vol.7, pp.532-541, 2014.

G. C. Leng, A. J. Lee, F. G. Fowkes, M. Whiteman, J. Dunbar et al., Incidence, natural history and cardiovascular events in symptomatic and asymptomatic peripheral arterial disease in the general population, Int J Epidemiol, vol.25, pp.1172-81, 1996.

B. Sigvant, F. Lundin, and E. Wahlberg, The risk of disease progression in peripheral arterial disease is higher than expected: a meta-analysis of mortality and disease progression in peripheral arterial disease, Eur J Vasc Endovasc Surg, vol.51, pp.395-403, 2016.

M. Kennedy, C. Solomon, T. A. Manolio, M. H. Criqui, A. B. Newman et al., Risk factors for declining ankle-brachial index in men and women 65 years or older: the Cardiovascular Health Study, Arch Intern Med, vol.165, pp.1896-902, 2005.

M. H. Criqui, J. K. Ninomiya, D. L. Wingard, M. Ji, and A. Fronek, Progression of peripheral arterial disease predicts cardiovascular disease morbidity and mortality, J Am Coll Cardiol, vol.52, pp.1736-1778, 2008.

A. T. Hirsch, Z. J. Haskal, N. R. Hertzer, C. W. Bakal, M. A. Creager et al., ACC/AHA 2005 guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): executive summary a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease) endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation

, National Heart, Lung, and Blood Institute

, Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation, J Am Coll Cardiol, vol.47, pp.1239-312, 2006.

A. B. Newman, D. S. Siscovick, T. A. Manolio, J. Polak, L. P. Fried et al., Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group, Circulation, vol.88, pp.837-882, 1993.

D. L. Bhatt, P. G. Steg, E. M. Ohman, A. T. Hirsch, Y. Ikeda et al., International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis, JAMA, vol.295, pp.180-189, 2006.

H. Vidula, L. Tian, K. Liu, M. H. Criqui, L. Ferrucci et al., Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study, Ann Intern Med, vol.148, pp.85-93, 2008.

P. G. Steg, D. L. Bhatt, P. W. Wilson, D. Sr, R. Ohman et al., One-year cardiovascular event rates in outpatients with atherothrombosis, JAMA, vol.297, pp.1197-206, 2007.