Comparative Performance of Anyplex II HPV28 and Cobas 4800 Human Papillomavirus (HPV) Assays for High-Risk HPV Detection in Self-collected Anal Samples

Gauthier Delvallez (1) , Sokleaph Cheng (1) , Stéphane Marot (2, 3) , Gervillien Arnold Malonga (2, 3) , Théophile Cocherie (2, 3) , Steve Wignall (4) , Vincent Calvez (2, 3) , Sophat Phal (4) , Kem Vichet (5) , Anne-Geneviève Marcelin (2, 3) , Aude Jary (2, 3)

1 Institut Pasteur du Cambodge
2 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
3 CHU Pitié-Salpêtrière [AP-HP]
4 FHI - Family Health International
5 Men's Health Cambodia, Phnom Penh

We compared 2 human papillomavirus (HPV) assays to detect the 14 high-risk HPV (hrHPV) genotypes in self-collected anal samples. We found a good agreement and similar performance to detect HPV-16, HPV-18, and the 12 other hrHPV genotypes. The global performance to detect the 14 hrHPV genotypes was not significantly different between the 2 assays.

Mots clés: Anal lesions; self-sampling; HPV-testing; Anyplex II HPV28; Cobas 4800; HPV16; MSM; TWG; Cambodia

Domaines: Médecine humaine et pathologie

Gauthier Delvallez, Sokleaph Cheng, Stéphane Marot, Gervillien Arnold Malonga, Théophile Cocherie, et al.. Comparative Performance of Anyplex II HPV28 and Cobas 4800 Human Papillomavirus (HPV) Assays for High-Risk HPV Detection in Self-collected Anal Samples. Open Forum Infectious Diseases, 2023, 10 (11), pp.ofad540. ⟨10.1093/ofid/ofad540⟩. ⟨hal-04400991⟩