Microwave-assisted expeditious O-alkylation of meso-hydroxyphenylporphyrins

Vincent Chaleix (1) , Pierre Couleaud (2) , Vincent Sol (1) , Rachida Zerrouki (1) , Sandra Alves (3) , Pierre Krausz (1)

1 LCSN - Laboratoire de Chimie des Substances Naturelles
2 DCPR - Département de Chimie Physique des Réactions
3 SSFMB - Synthèse, Structure et Fonction de Molécules Bioactives

A mild method for O-alkylation of meso-hydroxyphenylporphyrin has been developed using microwave irradiation. This method is clean and efficient for many substrates and results in significant improvement in reaction yield and in a dramatic decrease in reaction time in comparison to thermal heating

Domaines: Chimie organique

Vincent Chaleix, Pierre Couleaud, Vincent Sol, Rachida Zerrouki, Sandra Alves, et al.. Microwave-assisted expeditious O-alkylation of meso-hydroxyphenylporphyrins. Journal of Porphyrins and Phthalocyanines, 2009, 13 (8-9), pp.888-892. ⟨10.1142/S1088424609001157⟩. ⟨hal-00696084⟩