Multilocus Variable-Number Tandem-Repeat Analysis-Confirmed Emergence of a Macrolide Resistance-Associated Mutation in Mycoplasma pneumoniae during Macrolide Therapy for Interstitial Pneumonia in an Immunocompromised Child

Abstract : A child with Job's syndrome was treated for pneumonia due to Mycoplasma pneumoniae. A mixed population of wild-type bacteria and an A2059G mutant was detected during josamycin treatment failure. The same multilocus variable-number tandem-repeat analysis (MLVA) type (MLVA type I) was isolated before and after treatment failure. The child recovered after ciprofloxacin treatment.
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Journal of Clinical Microbiology, American Society for Microbiology, 2012, 50 (10), pp.3402-3405. 〈10.1128/jcm.01248-12〉
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Sébastien Hantz, Fabien Garnier, Olivia Peuchant, Céline Menetrey, Alain Charron, et al.. Multilocus Variable-Number Tandem-Repeat Analysis-Confirmed Emergence of a Macrolide Resistance-Associated Mutation in Mycoplasma pneumoniae during Macrolide Therapy for Interstitial Pneumonia in an Immunocompromised Child. Journal of Clinical Microbiology, American Society for Microbiology, 2012, 50 (10), pp.3402-3405. 〈10.1128/jcm.01248-12〉. 〈hal-01500787〉

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