Estimating the association between being seropositive for cysticercosis and the prevalence of epilepsy and severe chronic headaches in 60 villages of rural Burkina Faso

Ida Sahlu (1) , Hélène Carabin (2) , Rasmané Ganaba (3) , Pierre-Marie Preux (4, 5, 6) , Assana Kone Cissé (7) , Zékiba Tarnagda (7) , Sarah Gabriël (8) , Véronique Dermauw (9) , Pierre Dorny (9) , Cici Bauer (10) , Athanase Millogo (4, 11)

1 Department of Epidemiology [Brown University School of Public Health]
2 Department of Biostastistics and Epidemiology [University of Oklahoma Health Sciences Center]
3 AFRICSanté - Agence de Formation de Recherche et d'expertise en Santé pour l'Afrique
4 NET - Neuroépidémiologie Tropicale
5 SIME - Service de l'Information Médicale et de l'Évaluation [CHU Limoges]
6 Laboratoire de Biostatistique et d'Informatique Médicale
7 INSSA - Institut de Recherche en Sciences de la Santé Bobo Dioulasso
8 Research Group Veterinary Public Health and Zoonoses, Department of Veterinary Public Health and Food Safety, Laboratorium of Chemical Analysis
9 Department of Biomedical Sciences [Antwerp]
10 Department of Biostatistics [Houston]
11 CHUSS - Centre Hospitalier Universitaire Souro Sanou [Bobo-Dioulasso]

Individuals diagnosed with neurocysticercosis often present with epilepsy and sometimes with progressively worsening severe chronic headaches (WSCH). While cross-sectional associations between seropositivity to cysticercal antigens and epilepsy have been reported, few large scale studies have been conducted in West Africa and none have measured the association between seropositivity to cysticercal antigens and headaches. This study aimed at filling these knowledge gaps by estimating the strength of the cross-sectional association between seropositivity to cysticercal antigens and the prevalence of epilepsy and WSCH in 60 villages of Burkina Faso, West Africa.

Domaines: Santé publique et épidémiologie

Ida Sahlu, Hélène Carabin, Rasmané Ganaba, Pierre-Marie Preux, Assana Kone Cissé, et al.. Estimating the association between being seropositive for cysticercosis and the prevalence of epilepsy and severe chronic headaches in 60 villages of rural Burkina Faso. PLoS Neglected Tropical Diseases, 2019, 13 (1), pp.e0007101. ⟨10.1371/journal.pntd.0007101⟩. ⟨hal-02022991⟩